| Scout | Attribute | control |
|---|---|---|
| control_01 | ||
| Pi/MW Estimation | Pi | 5.70 |
| MW | 37190 | |
| Label name(s) | CysK | |
| GenoList | ||
| Gene Size (bp) |
924
|
|
| Isoelectric Point |
5.492
|
|
| Molecular Weight (Da) |
32666.0
|
|
| Protein Size (aa) |
308
|
|
| Function | ||
| Uniprot | ||
| Accession |
P37887
|
|
| Amino Acids |
308
|
|
| Function |
Catalyzes the conversion of O-acetylserine to cysteine. Also acts as a sensor of cysteine availability in the signal transduction pathway modulating CymR activity. When cysteine is present, the pool of O-acetylserine (OAS) is low, which leads to the formation of a CymR-CysK complex and transcriptional repression of the CymR regulon occurs. In the absence of cysteine, the OAS pool is high and the CymR-CysK complex is mostly dissociated, leading to a faster dissociation of CymR from its DNA targets and the lifting of CymR-dependent repression.
|
|
| Gene name |
cysK
|
|
| Gene Ontology |
|
|
| Isoelectric Point |
5.512
|
|
| Keywords | ||
| Molecular Weight |
32819.5
|
|
| NCBI Taxonomy |
1423
|
|
| Organism |
Bacillus subtilis
|
|
| Original label name |
CysK
|
|
| Protein name |
Cysteine synthase
|
|
| Query text |
CysK
|
|
| References | ||
| Sequence |
MVRVANSITELIGNTPIVKLNRLADENSADVYLKLEYMNPGSSVKDRIGLAMIEAAEKEG
KLKAGNTIIEPTSGNTGIGLAMVAAAKGLKAILVMPDTMSMERRNLLRAYGAELVLTPGA
EGMKGAIKKAEELAEKHGYFVPQQFNNPSNPEIHRQTTGKEIVEQFGDDQLDAFVAGIGT
GGTITGAGEVLKEAYPSIKIYAVEPSDSPVLSGGKPGPHKIQGIGAGFVPDILNTEVYDE
IFPVKNEEAFEYARRAAREEGILGGISSGAAIYAALQVAKKLGKGKKVLAIIPSNGERYL
STPLYQFD
|
|
| Title |
CYSK_BACSU
|
|
| Uniprot entry | ||
| AureoList | ||
| Gene Size (bp) |
933
|
|
| Isoelectric Point |
5.1289
|
|
| Molecular Weight (Da) |
32975.6
|
|
| Protein Size (aa) |
310
|
